EN
X
Research Papers
Challenging, professional and creative talent driving the future
Research Papers
Gas Plasma Treatment Improves Titanium Dental Implant Osseointegration—A Preclinical In Vivo Experim
Writer : plasmapp(business@plasmapp.com) Date : 2023-12-28 Hits : 163
Article Link : https://doi.org/10.3390/bioengineering10101181

Gas Plasma Treatment Improves Titanium Dental Implant Osseointegration—A Preclinical In Vivo Experimental Study 


Recent technological advancements led to the development of various plasma-based technologies for post-packaging modifications. The purpose of the present preclinical in vivo study was to assess the safety and efficacy of a novel chairside nonthermal gas plasma treatment for enhancing osseointegration of titanium implants. Six male mixed foxhounds underwent extraction of mandibular premolars and first molars, and the sockets healed for 42 days. Canine mandibles were randomized to receive either plasma-treated (test) or non-plasma-treated (control) dental implants. A total of 36 implants were placed in six animals, and they were sacrificed at 2 weeks (two animals), 4 weeks (two animals), and 6 weeks (two animals) after the implant surgery. When the radiographic analysis was performed, the changes in bone level were not statistically significant between the two groups at 2 weeks and 4 weeks. The difference became significant at 6 weeks (p = 0.016), indicating more bone loss from baseline to 6 weeks for the control group. The bone-to-implant contact (BIC) appeared to be higher for the test groups at all time points, and the BIC was significantly higher for the test group at 4 weeks (p = 0.046). In conclusion, this study underscored the potential of nonthermal plasma treatment in enhancing implant osseointegration.


▶ Statistical analysis demonstrating a significant difference in BIC between control and test implants at week 4.




Nevins, Myron, et al. "Gas Plasma Treatment Improves Titanium Dental Implant Osseointegration—A Preclinical In Vivo Experimental Study." Bioengineering 10.10 (2023): 1181.
 

Prev. Vacuum Plasma Treatment Device for Enhancing Fibroblast Activity on Machined and Rough Titanium Surf
Next Enhanced Osteoblast Adhesion and Proliferation on Vacuum Plasma-Treated Implant Surface